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Addressing Treatment-Resistant Depression

For many people, antidepressants are an effective treatment for depression. However, there is a subset of individuals who do not respond to traditional antidepressant medication and continue to experience symptoms of depression despite trying multiple types of medication. This condition is known as treatment-resistant depression (TRD). It can be frustrating to not see improvement in symptoms after trying numerous treatments, but it’s important to know that there are still options available.

Northeast Health Services provides mental health services for treatment-resistant depression that include transcranial magnetic stimulation (TMS) and Spravato® treatment. Call 508.794.8711 today to learn more about Spravato® treatment in our Worcester location.

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they eat as a way to kind of comfort during depression
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and eat more than they should.
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So depression can be more prevalent in women.
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Just because there is a hormonal component.
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So women are going through their menstrual cycle,
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there’s actually a diagnosis that’s known
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as premenstrual dysphoric syndrome,
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where we have more depression and mood symptoms.
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It’s also common after women of childbearing age
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have a child, they can experience postpartum depression as well.
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Treatment resistant depression is depression
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that has not responded to one or more oral antidepressants.
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So we always first line treat depression
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with an antidepressant most of the time,
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and that is with one of the classes, either an SSRI or an SNRI.
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When these medicines, when we try these medicines and they’re not working as well,
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then we go to alternative options to treat that depression
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and that depression can be labeled as treatment resistant depression.

The Difference Between Treatment-Resistant Depression and Other Types of Depression

Depression is a complex mental health condition that affects individuals in different ways. There are a number of different types of depression, including:

  • Major depressive disorder – Characterized by persistent feelings of sadness and hopelessness, loss of interest in activities, changes in appetite and sleep patterns, and difficulty concentrating.
  • Persistent depressive disorder – A chronic form of depression where symptoms are less severe but last for a longer period of time (at least two years).
  • Postpartum depression – Occurs after giving birth and is characterized by mood swings, anxiety, and difficulty bonding with the baby.
  • Seasonal affective disorder – A type of depression that occurs during certain seasons, most commonly in the fall and winter months.

While treatment-resistant depression is a form of major depressive disorder, it is differentiated by its resistance to traditional antidepressant medication. Other types of depression may respond well to medication and therapy, but for those with TRD, alternative treatments are necessary.

Is There a Solution for Treatment-Resistant Depression?

Fortunately, there are effective treatments available for those with treatment-resistant depression. Working with a mental health professional for an accurate diagnosis is the first step. This might involve trying different types of antidepressants, psychotherapy, and lifestyle changes. For individuals who continue to experience symptoms despite these efforts, transcranial magnetic stimulation (TMS) and Spravato® treatment are evidence-based options that have shown promising results.

Transcranial Magnetic Stimulation (TMS)

Transcranial magnetic stimulation is a non-invasive procedure that uses magnetic pulses to stimulate nerve cells in the brain. This can help regulate mood and reduce symptoms of depression. TMS is typically administered over a period of several weeks, with sessions lasting about 20 minutes. It has been shown to be effective for individuals with TRD who have not responded well to traditional antidepressant medication.

Spravato® Treatment

Spravato® (esketamine) is an intranasal spray that contains esketamine, which works on different brain receptors than traditional antidepressants. Spravato® has been shown to provide rapid relief of symptoms and can be used in conjunction with other treatments like therapy and medication management.

Both TMS and Spravato® treatment have been approved by the FDA for use in individuals with treatment-resistant depression. Often, these treatments are paired with therapy to help clients build healthy coping skills and address any underlying issues.

Contact Northeast Health Services Today for Help with Treatment-Resistant Depression

If you or a loved one is struggling with treatment-resistant depression, know that you are not alone. There are treatment options available that can help you find relief. Whether it’s through traditional medication management, TMS, or Spravato® treatment, our team at Northeast Health Services is here to support you. With locations throughout Massachusetts, we are dedicated to helping clients find the right treatment for their unique needs.

If you’re ready to take the next step in your mental health journey, click here to reach out to our team of empathetic mental health care experts. For existing clients, please click here and find your office location to contact your office directly.